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1. Company Snapshot

1.a. Company Description

MeiraGTx Holdings plc, a clinical stage gene therapy company, focusing on developing treatments for patients with serious diseases.The company develops various therapies for ocular diseases, including inherited blindness, as well as Xerostomia following radiation treatment for head and neck cancers; degenerative diseases; neurodegenerative diseases, such as amyotrophic lateral sclerosis; and Parkinson's diseases.Its programs in clinical development include Phase 1/2 clinical stage programs in Achromatopsia, X-Linked Retinitis Pigmentosa, RPE65-deficiency, and radiation-induced Xerostomia, as well as Parkinson's program.


The company also focuses on initiating a clinical program in xerostomia related to Sjogren's syndrome and have preclinical programs in neurodegenerative diseases.It has a research collaboration agreement with Janssen Pharmaceuticals, Inc.to develop regulatable gene therapy treatment using the company's proprietary riboswitch technology.


MeiraGTx Holdings plc was incorporated in 2015 and is based in New York, New York.

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1.b. Last Insights on MGTX

MeiraGTx Holdings plc faced negative drivers over the recent 3 months. Despite a "Moderate Buy" consensus rating from analysts, with four buy ratings and one strong buy, two analysts rated the stock with a sell rating. The company entered into an exclusive license agreement with ZipBio to advance a first-in-class AAV gene therapy for Geographic Atrophy. However, no recent earnings release data is available. Institutional investor AMH Equity Ltd acquired a new stake in MeiraGTx, purchasing 80,000 shares valued at $658,000 (AMH Equity Ltd, 2026).

1.c. Company Highlights

2. Transcript Summary

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3. NewsRoom

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MeiraGTx Holdings PLC (NASDAQ:MGTX) Receives Average Rating of “Moderate Buy” from Analysts

Feb -19

Source: defenseworld.net

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ZipBio and MeiraGTx Enter into Exclusive License Agreement to Advance First-in-Class AAV Gene Therapy for Geographic Atrophy

Feb -03

Source: prnewswire.com

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AMH Equity Ltd Invests $658,000 in MeiraGTx Holdings PLC $MGTX

Jan -18

Source: defenseworld.net

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MeiraGTx Holdings PLC (NASDAQ:MGTX) Given Average Rating of “Moderate Buy” by Analysts

Dec -31

Source: defenseworld.net

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Graviton Bioscience to Present Selective ROCK2 Obesity Data at 8th Annual Evercore HealthCONx Conference

Nov -20

Source: prnewswire.com

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MeiraGTx Holdings PLC (MGTX) Reports Q3 Loss, Lags Revenue Estimates

Nov -13

Source: zacks.com

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MeiraGTx Reports Third Quarter 2025 Financial and Operational Results

Nov -13

Source: globenewswire.com

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MeiraGTx: Latest Eli Lilly Partnership Ignites Riboswitch Technology Potential

Nov -12

Source: seekingalpha.com

4. Business Breakdown

4.a. Revenues by Country

4.b. Revenues by Segment

5. Expected revenues mid-term growth (9.03%)

6. Segments

Retinal Drugs and Gene Therapies

Expected Growth: 9.03%

MeiraGTx Holdings plc's Retinal Drugs and Gene Therapies segment growth is driven by increasing prevalence of inherited retinal diseases, advancements in gene therapy technology, and strong clinical trial results. Growing demand for novel treatments, strategic partnerships, and expanding product pipeline also contribute to the 9.03% growth.

7. Detailed Products

AAV-RPGR

Gene therapy for the treatment of X-linked retinitis pigmentosa

AAV-CNGB3

Gene therapy for the treatment of achromatopsia

AAV-RHO

Gene therapy for the treatment of rhodopsin-mediated autosomal dominant retinitis pigmentosa

AAV-ND4

Gene therapy for the treatment of Leber hereditary optic neuropathy

AAV-GAD

Gene therapy for the treatment of Parkinson's disease

AAV-FLT1

Gene therapy for the treatment of wet age-related macular degeneration

8. MeiraGTx Holdings plc's Porter Forces

Forces Ranking

Threat Of Substitutes

MeiraGTx Holdings plc operates in the biotechnology industry, which is characterized by high research and development costs. While there are substitutes available, they are not easily accessible, and the company's products are differentiated, reducing the threat of substitutes.

Bargaining Power Of Customers

MeiraGTx Holdings plc's customers are primarily pharmaceutical companies and research institutions, which have limited bargaining power due to the company's specialized products and services.

Bargaining Power Of Suppliers

MeiraGTx Holdings plc relies on a few key suppliers for raw materials and equipment, giving them some bargaining power. However, the company's specialized products and services reduce the suppliers' negotiating power.

Threat Of New Entrants

The biotechnology industry is highly competitive, and new entrants can easily disrupt the market. MeiraGTx Holdings plc's intellectual property and specialized products provide some barriers to entry, but new entrants can still pose a significant threat.

Intensity Of Rivalry

The biotechnology industry is highly competitive, with many established players and new entrants vying for market share. MeiraGTx Holdings plc faces intense competition from companies with similar products and services.

9. SWOT Analysis

Strength

Weaknesses

Opportunities

Threats

10. Capital Structure

10.a. Balance Sheet

10.b. Weighted Average Cost of capital

Value
Debt Weight 35.58%
Debt Cost 10.48%
Equity Weight 64.42%
Equity Cost 10.48%
WACC 10.48%
Leverage 55.23%

11. Quality Control: MeiraGTx Holdings plc passed 2 out of 9 key points

12.a Historical Valuation

12.b Price/Earnings Ratio

12.c Margin Valuation

12.d Peers Valuation

Peers Group Analysis

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Peers Metrics

12.e Scoring Insights

12.f DCF BETA

Parameters

Short Term Growth

Short term Time

Long-Term Growth

WACC

Target Price

7.43$

Current Price

7.43$

Potential

-0.00%

Expected Cash-Flows