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1. Company Snapshot

1.a. Company Description

AbbVie Inc.discovers, develops, manufactures, and sells pharmaceuticals in the worldwide.The company offers HUMIRA, a therapy administered as an injection for autoimmune and intestinal Behçet's diseases; SKYRIZI to treat moderate to severe plaque psoriasis in adults; RINVOQ, a JAK inhibitor for the treatment of moderate to severe active rheumatoid arthritis in adult patients; IMBRUVICA to treat adult patients with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and VENCLEXTA, a BCL-2 inhibitor used to treat adults with CLL or SLL; and MAVYRET to treat patients with chronic HCV genotype 1-6 infection.


It also provides CREON, a pancreatic enzyme therapy for exocrine pancreatic insufficiency; Synthroid used in the treatment of hypothyroidism; Linzess/Constella to treat irritable bowel syndrome with constipation and chronic idiopathic constipation; Lupron for the palliative treatment of advanced prostate cancer, endometriosis and central precocious puberty, and patients with anemia caused by uterine fibroids; and Botox therapeutic.In addition, the company offers ORILISSA, a nonpeptide small molecule gonadotropin-releasing hormone antagonist for women with moderate to severe endometriosis pain; Duopa and Duodopa, a levodopa-carbidopa intestinal gel to treat Parkinson's disease; Lumigan/Ganfort, a bimatoprost ophthalmic solution for the reduction of elevated intraocular pressure (IOP) in patients with open angle glaucoma (OAG) or ocular hypertension; Ubrelvy to treat migraine with or without aura in adults; Alphagan/ Combigan, an alpha-adrenergic receptor agonist for the reduction of IOP in patients with OAG; and Restasis, a calcineurin inhibitor immunosuppressant to increase tear production, as well as other eye care products.AbbVie Inc.


has a research collaboration with Dragonfly Therapeutics, Inc.The company was incorporated in 2012 and is headquartered in North Chicago, Illinois.

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1.b. Last Insights on ABBV

Negative drivers include escalating medical care costs and a decelerating growth trend. AbbVie's latest dividend raise signals near-term earnings pressure, with a 5.5% YOY increase lagging past growth rates. The company's valuation appears stretched, with a P/E ratio of 23.5x and a PEGY ratio of 1.41x, according to its Hold rating. Institutional investors, such as Commerzbank Aktiengesellschaft FI, have reduced their holdings, selling 39,586 shares.

1.c. Company Highlights

2. AbbVie's Q4 2025 Earnings: A Strong Close to an Excellent Year

AbbVie's fourth quarter 2025 performance closed out an excellent year, with record net sales and exceeding financial commitments. The company delivered adjusted earnings per share of $2.71, beating analyst estimates of $2.65. Total net revenues were $16.6 billion, reflecting robust growth of 10%. The company's full-year adjusted earnings per share guidance is between $14.37 and $14.57, and it expects total net revenues of approximately $67 billion in 2026.

Publication Date: Feb -05

📋 Highlights
  • Record Net Sales Growth: AbbVie achieved $61.2 billion in 2025 revenue, surpassing guidance by $2 billion, with 8.6% sales growth despite $16 billion in HUMIRA erosion.
  • Adjusted EPS Exceeded Guidance: Full-year adjusted EPS reached $10, outperforming initial guidance by $0.54, reflecting strong operational execution.
  • Significant R&D Investment: Adjusted R&D expenses rose by nearly $1 billion, funding 90 clinical programs, alongside $5 billion in business development for new assets like in vivo CAR-T and psychedelics.
  • 2026 Guidance Confirmed: The company targets $67 billion in total net revenues, 9.5% sales growth, and 48.5% adjusted operating margin, with Parkinson’s treatment Vialev expected to reach blockbuster status.
  • Immunology Dominance: SKYRIZI and RINVOQ generated $25.9 billion in 2025, with SKYRIZI capturing 75% of IBD frontline treatment and over 45% of psoriasis market share in the US.

Immunology Segment Performance

AbbVie's immunology segment delivered strong performance, driven by SKYRIZI and RINVOQ. The combined revenue of these two products was approximately $25.9 billion in 2025. SKYRIZI captured over 45% of the US biologic psoriasis market, while RINVOQ achieved a leading mid-teen in-play patient share for RA. The company expects continued double-digit revenue growth from these products, with combined sales of over $31 billion in 2026.

Neuroscience Segment Performance

AbbVie's neuroscience segment delivered full-year revenues of over $10.7 billion, driven by continued double-digit growth of Vraylar and Therapeutic. The company's emerging portfolio in Parkinson's disease, including Violet, is expected to achieve blockbuster revenue in 2026. The company is also making progress in its migraine business, with UBRELVY leading in acute migraine and Botox approved for chronic migraine.

Oncology Segment Performance

AbbVie's oncology segment delivered total revenues of nearly $1.7 billion in the quarter, with VENCLEXTA global sales up 6.4% on an operational basis. The company is making progress in its oncology pipeline, including a new PD-one VEGF antibody and a T cell engager. The company is also exploring the use of combinations with SKYRIZI, including alpha four beta seven and TL1A.

Valuation Metrics

Using the provided valuation metrics, we can see that AbbVie's P/E Ratio is 161.11, indicating a relatively high valuation. The company's P/S Ratio is 6.43, which is more reasonable. The Dividend Yield is 3.06%, which is attractive for income investors. The EV/EBITDA ratio is 34.92, which is relatively high. Overall, the valuation metrics suggest that AbbVie's stock price may be driven by its growth prospects, particularly in its immunology and neuroscience segments.

Growth Prospects

AbbVie has numerous sources of upside across the enterprise, including immunology, neuroscience, and oncology. The company expects SKYRIZI and RINVOQ to grow robustly into the 2030s, with longer-term growth not reflected in models. The neuroscience segment is expected to deliver mid-teens growth this year, with the Parkinson's franchise achieving peak sales in excess of $5 billion. Analysts estimate next year's revenue growth at 7.8%, which is slightly lower than the company's expected growth rate.

3. NewsRoom

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Dividend Kings: No Ideal Buys In February's 57

Feb -10

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Here's What Will Drive AbbVie's Top-line Growth in 2026

Feb -10

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Legacy Financial Strategies LLC Sells 12,664 Shares of AbbVie Inc. $ABBV

Feb -09

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AbbVie Inc. $ABBV Shares Sold by Profund Advisors LLC

Feb -09

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AbbVie's Prognosis: The February Dip Looks Like a Buy Signal

Feb -05

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AbbVie: The Market Is Getting It Wrong

Feb -05

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AbbVie: Skyrizi And Rinvoq Growth Isn't Everything, But It's A Lot

Feb -05

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AbbVie: Double-Digit Growth For Immunology Products Continues With HUMIRA Surprise

Feb -04

4. Business Breakdown

4.a. Revenues by Country

4.b. Revenues by Segment

5. Expected revenues mid-term growth (10.30%)

6. Segments

Innovative Medicines and Therapies

Expected Growth: 10.3%

AbbVie's biopharmaceuticals' growth is driven by increasing demand for innovative therapies, strong R&D pipeline, and strategic collaborations, leading to a forecasted 10.3% growth rate.

7. Detailed Products

Humira

Humira is a prescription medication used to treat autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, and ulcerative colitis.

Imbruvica

Imbruvica is a prescription medication used to treat certain types of blood cancers, including mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström's macroglobulinemia.

Venclexta

Venclexta is a prescription medication used to treat chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML).

Mavyret

Mavyret is a prescription medication used to treat chronic hepatitis C virus (HCV) infection.

Rinvoq

Rinvoq is a prescription medication used to treat moderate to severe rheumatoid arthritis.

Skyrizi

Skyrizi is a prescription medication used to treat moderate to severe plaque psoriasis.

Ubrelvy

Ubrelvy is a prescription medication used to treat acute migraine attacks.

8. AbbVie Inc.'s Porter Forces

Forces Ranking

Threat Of Substitutes

AbbVie Inc. has a moderate threat of substitutes due to the presence of alternative treatments and therapies for various diseases. However, the company's strong brand recognition and patented products mitigate this threat to some extent.

Bargaining Power Of Customers

AbbVie Inc. has a low bargaining power of customers due to the lack of concentration in the buyer's market. The company's products are often prescribed by doctors, reducing the bargaining power of individual customers.

Bargaining Power Of Suppliers

AbbVie Inc. has a moderate bargaining power of suppliers due to the presence of multiple suppliers for raw materials and services. However, the company's large scale of operations and long-term contracts with suppliers mitigate this threat to some extent.

Threat Of New Entrants

AbbVie Inc. has a low threat of new entrants due to the high barriers to entry in the pharmaceutical industry, including significant R&D investments and regulatory hurdles.

Intensity Of Rivalry

AbbVie Inc. operates in a highly competitive pharmaceutical industry, with many established players and new entrants vying for market share. The company faces intense competition in various therapeutic areas, including immunology, oncology, and virology.

9. SWOT Analysis

10. Capital Structure

10.a. Balance Sheet

10.b. Weighted Average Cost of capital

Value
Debt Weight 85.15%
Debt Cost 3.95%
Equity Weight 14.85%
Equity Cost 7.07%
WACC 4.41%
Leverage 573.21%

11. Quality Control: AbbVie Inc. passed 6 out of 9 key points

12.a Historical Valuation

12.b Price/Earnings Ratio

12.c Margin Valuation

12.d Peers Valuation

Peers Group Analysis

Stock-Card
J&J

A-Score: 6.9/10

Value: 3.1

Growth: 4.0

Quality: 8.8

Yield: 6.0

Momentum: 9.5

Volatility: 10.0

1-Year Total Return ->

Stock-Card
Gilead Sciences

A-Score: 6.8/10

Value: 3.3

Growth: 3.0

Quality: 9.3

Yield: 7.0

Momentum: 9.5

Volatility: 8.3

1-Year Total Return ->

Stock-Card
AbbVie

A-Score: 6.7/10

Value: 3.1

Growth: 4.7

Quality: 7.2

Yield: 7.0

Momentum: 9.5

Volatility: 9.0

1-Year Total Return ->

Stock-Card
Amgen

A-Score: 6.3/10

Value: 2.9

Growth: 5.0

Quality: 6.8

Yield: 6.0

Momentum: 9.0

Volatility: 8.3

1-Year Total Return ->

Stock-Card
Merck

A-Score: 6.2/10

Value: 4.6

Growth: 6.2

Quality: 8.2

Yield: 6.0

Momentum: 4.5

Volatility: 8.0

1-Year Total Return ->

Stock-Card
Bristol-Myers Squibb

A-Score: 5.5/10

Value: 5.0

Growth: 3.9

Quality: 6.5

Yield: 8.0

Momentum: 1.5

Volatility: 8.0

1-Year Total Return ->

Peers Metrics

12.e Scoring Insights

12.f DCF BETA

Parameters

Short Term Growth

Short term Time

Long-Term Growth

WACC

Target Price

222.44$

Current Price

222.44$

Potential

-0.00%

Expected Cash-Flows